{{htmlmetatags>
metatag-keywords=(Syndromes gériatriques, Confusion, Psychogériatrie, Hospitalisation)
metatag-og:title=(Confusion. Wilson JE, et al, Nat Rev Dis Primers 2020.)
metatag-description=(Confusion. Wilson JE, et al, Nat Rev Dis Primers 2020.)
metatag-og:type=article
metatag-article:published_time=2021-01-10
metatag-article:modified_time=2021-03-07
}}
{{page>:priv:keywords&nofooter&noeditbtn}}
~~NOTOC~~
{{pmid>addtt:33184265|Confusion.}}
{{pmid>addhash_fr:33184265|Syndromes_gériatriques, Hospitalisation}}
====== Confusion. Wilson JE, et al, Nat Rev Dis Primers 2020. ======
{{tag>Syndromes_gériatriques Confusion Psychogériatrie}}
{{tag>Hospitalisation}}
* **Proposé le :** 10/01/2021 11:59
* **Par :** [[:user:formuser]]
* **Avec la version du site :**
* **Revu par :**
* //Mettre votre nom d'utilisateur//
* //Mettre votre nom d'utilisateur//
{{tag>Proposé_à_relecture 2021-01 Non_attribué Non_finalisé}}
{{page>:veille:info:part_authors_instructions&noindent&nolink&nofooter&noeditbtn}}
===== Résumé et points clés =====
Delirium, a syndrome characterized by an acute change in attention, awareness and cognition, is caused by a medical condition that cannot be better explained by a pre-existing neurocognitive disorder. Multiple predisposing factors (for example, pre-existing cognitive impairment) and precipitating factors (for example, urinary tract infection) for delirium have been described, with most patients having both types. Because multiple factors are implicated in the aetiology of delirium, there are likely several neurobiological processes that contribute to delirium pathogenesis, including neuroinflammation, brain vascular dysfunction, altered brain metabolism, neurotransmitter imbalance and impaired neuronal network connectivity. The Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) is the most commonly used diagnostic system upon which a reference standard diagnosis is made, although many other delirium screening tools have been developed given the impracticality of using the DSM-5 in many settings. Pharmacological treatments for delirium (such as antipsychotic drugs) are not effective, reflecting substantial gaps in our understanding of its pathophysiology. Currently, the best management strategies are multidomain interventions that focus on treating precipitating conditions, medication review, managing distress, mitigating complications and maintaining engagement to environmental issues. The effective implementation of delirium detection, treatment and prevention strategies remains a major challenge for health-care organizations globally.
===== Références de l'article =====
{{pmid>listgroup:33184265}}
----
{{page>:veille:pm:discussion:33184265&nofooter&nolink&noindent}}
[[:veille:pm:discussion:33184265?do=edit|Éditer la discussion]]