{{htmlmetatags>
metatag-keywords=(Fragilité)
metatag-og:title=(Age-Related Frailty: A Clinical Model for Geroscience? Takeda C, et al, J Nutr Health Aging 2020.)
metatag-description=(Age-Related Frailty: A Clinical Model for Geroscience? Takeda C, et al, J Nutr Health Aging 2020.)
metatag-og:type=article
metatag-article:published_time=2021-03-14
metatag-article:modified_time=2021-03-14
}}
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{{pmid>addtt:33244574|Age-Related Frailty: A Clinical Model for Geroscience?}}
{{pmid>addhash_fr:33244574|Fragilité}}
====== Age-Related Frailty: A Clinical Model for Geroscience? Takeda C, et al, J Nutr Health Aging 2020. ======
{{tag>Fragilité }}
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* **Proposé le :** 14/03/2021 09:07:04
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{{tag>Proposé_à_relecture 2021-03 Non_attribué Non_finalisé}}
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===== Résumé et points clés =====
In their everyday practice, geriatricians are confronted with the fact that older age and multimorbidity are associated to frailty. Indeed, if we take the example of a very old person with no diseases that progressively becomes frail with no other explanation, there is a natural temptation to link frailty to aging. On the other hand, when an old person with a medical history of diabetes, arthritis and congestive heart failure becomes frail there appears an obvious relationship between frailty and comorbidity. The unsolved question is: Considering that frailty is multifactorial and in the majority of cases comorbidity and aging are acting synergistically, can we disentangle the main contributor to the origin of frailty: disease or aging? We believe that it is important to be able to differentiate age-related frailty from frailty related to comorbidity. In fact, with the emergence of geroscience, the physiopathology, diagnosis, prognosis and treatment will probably have to be different in the future.
===== Références de l'article =====
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