{{htmlmetatags>
metatag-keywords=(COVID19, Mortalité, Présentation, Clinique)
metatag-og:title=(Clinical presentation and mortality in hospitalized patients aged 80+ years with COVID-19-A retrospective cohort study. Karlsson LK, et al, Arch Gerontol Geriatr 2020.)
metatag-description=(Clinical presentation and mortality in hospitalized patients aged 80+ years with COVID-19-A retrospective cohort study. Karlsson LK, et al, Arch Gerontol Geriatr 2020.)
metatag-og:type=article
metatag-article:published_time=2021-04-06
metatag-article:modified_time=2021-05-07
}}
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~~NOTOC~~
{{pmid>addtt:33476754|Clinical presentation and mortality in hospitalized patients aged 80+ years with COVID-19-A retrospective cohort study.}}
{{pmid>addhash_fr:33476754|COVID19, Mortalité, Présentation, Clinique}}
====== Clinical presentation and mortality in hospitalized patients aged 80+ years with COVID-19-A retrospective cohort study. Karlsson LK, et al, Arch Gerontol Geriatr 2020. ======
{{tag>COVID19 }}
{{tag>Mortalité, Présentation, Clinique}}
* **Proposé le :** 06/04/2021 08:07:05
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{{tag>Proposé_à_relecture 2021-04 Non_attribué Non_finalisé}}
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===== Résumé et points clés =====
**Background:** COVID-19, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has great health implications in older patients, including high mortality. In general, older patients often have atypical symptom presentations during acute illness due to a high level of comorbidity. The purpose of this study was to investigate the presentation of symptoms at hospital admissions in older patients with COVID-19 and evaluate its impact on disease outcome.
**Methods:** This retrospective study included patients ≥80 years of age with a positive test for SARS-CoV-2, who were admitted to one of three medical departments in Denmark from March 1st to June 1st, 2020.
**Results:** A total of 102 patients (47% male) with a mean age of 85 years were included. The most common symptoms at admission were fever (74%), cough (62%), and shortness of breath (54%). Furthermore, atypical symptoms like confusion (29%), difficulty walking (13%), and falls (8%) were also present. In-hospital and 30-day mortality were 31% (n = 32) and 41% (n = 42), respectively. Mortality was highest in patients with confusion (50% vs 38%) or falls (63% vs 39%), and nursing home residency prior to hospital admission was associated with higher mortality (OR 2.7, 95% CI 1.1-6.7).
**Conclusions:** Older patients with SARS-Cov-2 displayed classical symptoms of COVID-19 but also geriatric frailty symptoms such as confusion and walking impairments. Additionally, both in-hospital and 30-day mortality was very high. Our study highlights the need for preventive efforts to keep older people from getting COVID-19 and increased awareness of frailty among those with COVID-19.
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