Do specific delirium aetiologies have different associations with death? A longitudinal cohort of hospitalised patients. Chalmers LA, et al, Eur Geriatr Med 2021.
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Résumé et points clés
Purpose: To describe aetiology-specific associations with mortality among older hospital patients with delirium.
Methods: Over 21 months, a cohort of 1702 patients with 2471 acute hospital admissions (median age 85, IQR 80-90, 56% women) were assessed for delirium, categorised with inflammatory and metabolic aetiologies based on available laboratory results, and followed up for all-cause mortality. Interactions between aetiology and delirium were tested.
Results: The total mortality for the cohort was 35.2%. While inflammation, metabolic disturbance, and delirium at time of admission all demonstrated independent associations with mortality, there was no evidence for any interactions between delirium and these laboratory-measured aetiologies.
Conclusions: Delirium remains an important predictor of death in older hospital patients, irrespective of underlying aetiology.
Références de l'article
- Do specific delirium aetiologies have different associations with death? A longitudinal cohort of hospitalised patients.
- Do specific delirium aetiologies have different associations with death? A longitudinal cohort of hospitalised patients.
- Chalmers LA, Searle SD, Whitby J, Tsui A, Davis D
- European geriatric medicine
- 2021
- Eur Geriatr Med. 2021 Aug;12(4):787-791. doi: 10.1007/s41999-021-00474-8. Epub 2021 Mar 16.
- Aged, Aged, 80 and over, Causality, Cohort Studies, *Delirium/diagnosis, Female, Hospitalization, Humans, Inpatients, Male
- Syndromes_Geriatriques, Mortalité, Delirium
- Liens
- Traduction automatique en Français sur Google Translate
- DOI: 10.1007/s41999-021-00474-8
- PMID: 33725336
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